Martha Moody’s first novel, Best Friends, was a bestselling melodrama that followed the lifelong friendship of two privileged professional women. For her followup, Moody chose a subject and a setting closer to the ordinary experience of many of her fans: life in an office.

The Office of Desire is the story of three women who work together in a small medical practice in Ohio. The book is an intimate examination of the tangle of relations among people who would not necessarily have become friends if they had not been thrown together by work.

Stories about office workers are selling like hotcakes.

The popular comedy The Office begins its fourth season on NBC on September 27, while a new ABC series, Carpoolers, will premiere on October 2. But the two TV shows are just the tip of the iceberg. Books, movies, Web series, comics—all offer windows into the mundane realities, management crises, and emotional interplay of characters busy earning their daily bread.

Office romances, comedies, and dramas have been a staple of popular entertainment for decades, going back to cultural touchstones like The Man in the Gray Flannel Suit, How to Succeed in Business Without Really Trying, and The Mary Tyler Moore Show. More recently, a slew of novels (The Office of Desire, Then We Came to the End by Joshua Ferris, Company by Max Barry, and many more), movies (The Devil Wears Prada), and TV shows (The Apprentice, The West Wing) have revolved around tyrannical or incompetent bosses, annoying or amusing co-workers, and the business of work.

Meanwhile, The No Asshole Rule, Made to Stick, and a shelf’s worth of other nonfiction business books that aim to show readers how to be more effective and thus happier at work (and away from the office as well) are also riding high on bestseller lists.

And of course at 19 years and counting, Scott Adams’s Dilbert brand is going strong in print, online, and in the merchandising arena.

There are several reasons for the enduring appeal of office-related entertainment, according to critics and other culture watchers. For one thing, many people spend more time at work these days than they do with their families.

And in the 1950s and ’60s, women started to enter the workforce in greater numbers, a shift that gave new potential to the office as a setting, says Jeff Kloske, publisher of Riverhead Books, which released The Office of Desire last month. “Now, the thing is that people’s entire lives are defined by their office relationships,” he says. “That’s why the office as setting for all these different forms of entertainment is so successful.”

But although a growing proportion of Americans have white-collar jobs, that doesn’t mean they feel a greater sense of empowerment when they’re at their desks than an assembly-line worker does.

“There’s a certain amount of cynicism,” says David Halle, a sociology professor at the University of California, Los Angeles. “There are a lot of mergers, companies being bought and sold. People are sitting in their offices, and for the vast majority, there’s not much they can do about it.”